HIV-1 and TB co-infection skew the SARS-CoV-2 T cell response
SARS-CoV-2-specific CD4 T cell attributes, rather than magnitude, associate with disease severity, with severe disease being characterized by poor polyfunctional potential, reduced proliferation capacity and enhanced HLA-DR expression.
Image of scientist holding up a Petri dish
Supporting Excellence
The Wellcome Centre for Infectious Diseases Research in Africa fosters investigator-led approaches via the overarching scientific objective of combatting infection, especially HIV-1 and tuberculosis, through clinical and laboratory research.
Macrophages infected with M. tuberculosis; image by Dr Suraj Parihar
Basic Science
Our Basic Science Platform provides the laboratory infrastructure and technical support to ensure the safe handling of infectious material.
Subgraph of the ANIMA network for dataset HIVsetB
Biomedical Data Integration
We work with multidimensional clinical and scientific data at the molecular, cellular, clinical and population levels.
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Clinical Research
CIDRI-Africa supports clinical studies in the community at our facility at Site B in Khayelitsha.


Saturday, 15 May 2021
Cartoon of bacilli on a two-tone circular blue background
CIDRI-Africa welcomes Professor Marc Mendelson

Marc, who is Head of the Division of Infectious Diseases and HIV Medicine at the University of Cape Town, joins the Centre as a Contributing Investigator.

Publication Date:
Tue, 13 Oct 2020 - 12:15
Icon of a virus on a round two-tone blue background
CIDRI-Africa welcomes Dr Georgia Schäfer

Georgia joins the Centre as a Contributing Investigator, bringing expertise in oncogenic viral biology.

Publication Date:
Mon, 14 Sep 2020 - 11:30
R workshops aRen’t on hold

CIDRI-Africa biostatistician Olina Ngwenya adapts by transitioning to online R workshops.

Publication Date:
Tue, 11 Aug 2020 - 09:30
Image of coronavirus particles
CIDRI-Africa jump-starts six COVID-19 research projects

The projects cover a range of topics from treatment trials to diagnostics to serological analyses and answer several critical questions about the virus, the disease, and the pandemic.

Publication Date:
Mon, 03 Aug 2020 - 14:45